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The Cutting-Edge Science Behind SystemAge™

SystemAge uses 20 years of research by Dr. Irina Conboy to measure aging with organ-level precision with AI-powered Epigenetics.

Entropy Curve

BioNoise™

Biological Age

Where science meets longevity

The Gold Standard in Biological Age Testing

Clinically validated. Head-to-head tested.

Proven Accuracy Outperforming Competition

See how SystemAge stacks up in direct comparisons against traditional biological age clocks— and why doctors are standing behind it.

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Accuracy
Confidence (MMC)
Specificity (TNR)
Sensitivity
Negative Predictive Value (NPV)
F1-score (Best Metric for Clinical Balance)
SystemAge™
0.99
0.97
0.983
0.994
0.986
0.993
DunedinPACE
0.58
0.16
0.584
0.576
0.537
0.586
PhenoAge
0.57
0.14
0.573
0.568
0.568
0.571

Backed by World-Leading Scientists and Clinicians

Our science is backed by world-renowned scientists with cutting-edge research.

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Dr. Irina Conboy

CSO & Co-founder

Leading expert in aging research and regenerative biology. Dr. Conboy's groundbreaking work in cellular rejuvenation and aging mechanisms forms the foundation of our technology.

Dr. Conboy on Google Scholar →

Published Research

Our research has been published in leading journals and featured extensively in the media.

GeroScience

GeroScience - Jan 18, 2025

DNA methylation clocks struggle to distinguish inflammaging from healthy aging, but feature rectification improves coherence and enhances detection of inflammaging

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PubMed

PubMed - Dec 11, 2024

The dominance of old blood, and age-related increase in protein production and noise

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Aging

Aging - Sep 12, 2023

Fail-tests of DNA methylation clocks, and development of a noise barometer for measuring epigenetic pressure of aging and disease

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Cell Cycle

Cell Cycle - Jun 15, 2012

Heterochronic parabiosis for the study of the effects of aging on stem cells and their niches

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Cell Stem Cell

Cell Stem Cell - Jan 10, 2008

A Temporal Switch from Notch to Wnt Signaling in Muscle Stem Cells Is Necessary for Normal Adult Myogenesis

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Nature

Nature - Feb 17, 2005

Rejuvenation of aged progenitor cells by exposure to a young systemic environment

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Trusted by authorities in longevity science

Backed by World-Leading Scientists with Cutting-Edge Research

Experience the science

Discover your true biological age with our revolutionary testing technology.

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